Mean cell volume (MCV) Average volume of the red blood cell (RBC) Femtoliters (fL) or 10-15 Liter: Mean cell hemoglobin (MCH) Average weight of hemoglobin (Hb) in the RBC: Picograms (pg) or 10-12 grams: Mean cell hemoglobin concentration (MCHC) Average concentration of Hb in the RBC volume: Grams/deciliter (g/dL) If the MCV and/or MCH are high, it indicates macrocytic anemia, usually caused by either low B12 or low folate. If MCV and/or MCH are low, it indicates iron deficiency anemia. Symptoms of Anemia. Symptoms of either type of anemia include: Fatigue; A rapid heart beat (tachycardia) Palpitations; Shortness of breath; Headache; Dizziness; Pale skin The median of MCV, MCH, and MCHC in both patient with falciparum malaria and vivax malaria were significantly higher than those with non-malaria group (P value < 0.001). There was no significant association between status of malaria infection and MCV > 100fL, MCH > 32pg/cell, and MCHC >37g/dL cutoff value (P value > 0.05). Results showed that acetaminophen (200 mg/kg and 700 mg/kg) significantly increased MCV, MCH and decreased RBC and HB in a dose dependent manner with no significant effect on MCHC when compared to An RDW (red blood cell distribution width) blood test measures how varied your red blood cells are in size and volume. Your red blood cells carry oxygen from your lungs to organs and tissues throughout your body. The oxygen fuels your body’s cells so that they can produce energy. When it comes to your red blood cells, size matters. The MCH blood test, also known as Mean Corpuscular Hemoglobin, is a measurement of the average amount of hemoglobin in your red blood cells. Hemoglobin is a protein in your red blood cells that carries oxygen throughout your body. The MCH value is typically reported as part of a complete blood count (CBC) and can help diagnose and monitor MCH is derived from the Hb divided by RBC. Thus, for example, if there are 150 g of haemoglobin and 5 × 10 12 red cells per litre: MCH = 150 ÷ 5 × 10 12 = 3 ÷ 10 11 g = 30 picograms pg. The MCHC is derived in the traditional manner (see p. 24) from the Hb and the Hct with instruments that measure the Hct and calculate the MCV, whereas when Because the size of RBCs (MCV) determines the Hb content of RBCs (MCH), the higher the MCV/MCH, the higher the Hb and vice versa. Similarly, MCV is a principal contributor to Hct because Hct is a product of RBCs of certain sizes: Hct = RBC × MCV. This classic formula not only demonstrates how Hct is calculated (manually or by cell analyzers About the Parameters: Normal values (and limits) are expressed in C Units. Spcmn = specimen. Abbrev = abbreviation. CF= conversion factor. Units (c) x CF = Units (si) (unless otherwise specified). There can be various underlying reasons for the abnormality in the MCH or MCHC levels in red blood cells of an individual. Some include: 1. Anemia: Level of MCH or MCHC indicate the nature and severity of the anemia you have. Low levels of MCHC may indicate the possibility of hypochromic microcytic anemia. WhdHHU.